COVID-19 vaccine tracker


Researchers worldwide are working around the clock to find a vaccine against SARS-CoV-2, the virus causing the COVID-19 pandemic. The Herculean effort means that a fast-tracked vaccine could come to market anywhere from the end of 2020 to the middle of 2021.
To date, just two coronavirus vaccine has been approved. Sputnik V – formerly known as Gam-COVID-Vac and developed by the Gamaleya Research Institute in Moscow – was approved by the Ministry of Health of the Russian Federation on 11 August. Experts have raised considerable concern about the vaccine’s safety and efficacy given it has not yet entered Phase 3 clinical trials. A second vaccine in Russia, EpiVacCorona, has also been granted regulatory approval, also without entering Phase 3 clinical trials.
The pandemic has created unprecedented public/private partnerships. Operation Warp Speed (OWS) is a collaboration of several US federal government departments including Health and Human Services and its subagencies, Agriculture, Energy and Veterans Affairs and the private sector. OWS has selected three vaccine candidates to fund for Phase 3 trials: Moderna’s mRNA-1273, University of Oxford and AstraZeneca’s AZD1222, and Pfizer and BioNTech’s BNT162.
Within OWS, the US National Institutes of Health (NIH) has partnered with more than 18 biopharmaceutical companies to accelerate development of drug and vaccine candidates for COVID-19 (ACTIV). The COVID-19 Prevention Trials Network (COVPN) has also been established, which combines clinical trial networks funded by the National Institute of Allergy and Infectious Diseases (NIAID): the HIV Vaccine Trials Network (HVTN), HIV Prevention Trials Network (HPTN), Infectious Diseases Clinical Research Consortium (IDCRC), and the AIDS Clinical Trials Group.
The COVAX initiative, part of the World Health Organization’s (WHO) Access to COVID-19 Tools (ACT) Accelerator, is being spearheaded by the Coalition for Epidemic Preparedness Innovations (CEPI); Gavi, the Vaccine Alliance; and WHO. The goal is to work with vaccine manufacturers to offer low-cost COVID-19 vaccines to countries. Currently, CEPI’s candidates from companies Inovio, Moderna, CureVac, Institut Pasteur/Merck/Themis, AstraZeneca/University of Oxford, Novavax, University of Hong Kong, Clover Biopharmaceuticals, and University of Queensland/CSL are part of the COVAX initiative. There are further candidates being evaluated in the COVAX Facility from the United States and internationally.

Members of ACTIV have suggested developing safe controlled human infection models (CHIMs) for human trials could take 1-2 years. A sponsor would need to provide data from placebo-controlled trials indicating their vaccine is at least 50% effective against COVID-19 in order to be authorized for use, according to FDA guidance issued and effective 30 June, while the European Union’s chief drug regulator has suggested the EU would approve a vaccine with less than 50% efficacy. . Additional FDA guidance on COVID-19 vaccine EUAs was released 06 October. The guidance calls for interim analysis based on a clinical endpoint in a Phase 3 trial of at least 2 months in over 3,000 participants, as well as relevant safety and efficacy data from Phase 1 and Phase 2 trials.
This tracker lists COVID-19 vaccine candidates currently in Phase 1-3 trials, as well as major candidates in pre-clinical stages of development and research. To reveal in-depth information about each candidate, select the “Details” button below or click on the green plus button next to each entry.
Information will be updated weekly. If you notice an issue with this data or wish to submit an update, please email Focus at
Updated 09 November to include new information on the vaccine candidate from Pfizer/BioNTech. 

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CandidateMechanismSponsorTrial PhaseInstitution
BNT162mRNA-based vaccinePfizer, BioNTechPhase 3Multiple study sites in Europe and North America
Ad5-nCoVRecombinant vaccine (adenovirus type 5 vector)CanSino BiologicsPhase 3Tongji Hospital; Wuhan, China
AZD1222Replication-deficient viral vector vaccine (adenovirus from chimpanzees)The University of Oxford; AstraZeneca; IQVIA; Serum Institute of IndiaPhase 3The University of Oxfordthe Jenner Institute
CoronaVacInactivated vaccine (formalin with alum adjuvant)SinovacPhase 3Sinovac Research and Development Co., Ltd.
CovaxinInactivated vaccineBharat Biotech; National Institute of VirologyPhase 3
JNJ-78436735 (formerly Ad26.COV2.S)Non-replicating viral vectorJohnson & JohnsonPhase 3Johnson & Johnson
mRNA-1273mRNA-based vaccineModernaPhase 3Kaiser Permanente Washington Health Research Institute
No name announcedInactivated vaccineWuhan Institute of Biological Products; China National Pharmaceutical Group (Sinopharm)Phase 3Henan Provincial Center for Disease Control and Prevention
NVX-CoV2373Nanoparticle vaccineNovavaxPhase 3Novavax
Bacillus Calmette-Guerin (BCG) vaccineLive-attenuated vaccineUniversity of Melbourne and Murdoch Children’s Research InstituteRadboud University Medical CenterFaustman Lab at Massachusetts General HospitalPhase 2/3University of Melbourne and Murdoch Children’s Research InstituteRadboud University Medical CenterFaustman Lab at Massachusetts General Hospital

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